| Autor: |
Cas Stefaan Dejonckheere, Egon Dejonckheere, Julian Philipp Layer, Katharina Layer, Gustavo Renato Sarria, David Koch, Alina Abramian, Christina Kaiser, Kira Lindner, Anne Bachmann, Teresa Anzböck, Fred Röhner, Frederic Carsten Schmeel, Leonard Christopher Schmeel |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Breast, Vol 71, Iss , Pp 31-41 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1532-3080 |
| DOI: |
10.1016/j.breast.2023.07.001 |
| Popis: |
Purpose: Radiation dermatitis (RD) is the most common side effect of adjuvant whole-breast or chest wall irradiation, majorly impacting quality of life in numerous patients. The use of barrier films (polyurethane dressings such as Hydrofilm® and Mepitel® film remaining on the skin for the duration of the radiation treatment) has been investigated as a prophylactic measure in several prospective trials. Here, we critically appraise the available evidence behind preventive barrier film application in the context of breast cancer treatment. Methods: International literature was reviewed and high-quality randomised controlled trials (RCTs) were included in this meta-analysis. Results: The results of 5 RCTs (663 patients; >90% Caucasian) were analysed. Overall, barrier films lead to improved clinician- and patient-reported outcomes: fewer grade ≥2 RD (11% vs. 42%; OR = 0.16; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect