The significance of anti-phospholipase receptor antibodies in a patient with membranous nephropathy

Autor: Jayaprakash R Dasari, Pallavi Reddy, Yeshwanter Radhakrishnan, Nikhil Nair, Ronith Chakraborty, Lena Nemer, Rupesh Raina
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Saudi Journal of Kidney Diseases and Transplantation, Vol 31, Iss 6, Pp 1415-1419 (2020)
Druh dokumentu: article
ISSN: 1319-2442
DOI: 10.4103/1319-2442.308360
Popis: Membranous nephropathy (MN) is the major cause of nephrotic syndrome in adults and may be secondary to systemic lupus erythematosus or malignancy in 25% of patients. Without any etiology, it is called primary MN, which is usually associated with phospholipase A2 (PLA2) receptor antibodies. Secondary MN can appear months before a secondary cause is identified. Here, we report a case of MN, that was found to be secondary to pancreatic adenocarcinoma and positive for PLA2 receptor antibodies.
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