Correlation of microrna-372 upregulation with poor prognosis in human glioma

Autor: Li Gang, Zhang Zhiguo, Tu Yanyang, Jin Tianbo, Liang Hongjuan, Cui Guangbin, He Shiming, Gao Guodong
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Diagnostic Pathology, Vol 8, Iss 1, p 1 (2013)
Druh dokumentu: article
ISSN: 1746-1596
DOI: 10.1186/1746-1596-8-1
Popis: Abstract MicroRNA-372 (miR-372) acts as either an oncogenic miRNA or an anti-oncomiR in various human malignancies. However, its roles in gliomas have not been elucidated. To address this problem, we here detected miR-372 expression in human gliomas and non-neoplastic brain tissues by real-time quantitative RT-PCR assay. The association of miR-372 expression with clinicopathological factors or prognosis of glioma patients was also statistically analyzed. As the results, miR-372 expression levels were significantly upregulated in glioma tissues compared to the corresponding non-neoplastic brain tissues (P Virtual slides The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1707761328850011
Databáze: Directory of Open Access Journals