Comparison of Toxicities Associated with Concomitant Boost and Conventional Fractionated Radiotherapy Regimen in Oral and Oropharyngeal Cancers
| Autor: | Abhishek Shrivastava, Hameeduzzafar Ghori, Omprakash Singh, Vivek Tiwari, Veenita Yogi, Ramsingh Jamre, Varsha Mandloi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 11, Iss 10, Pp XC01-XC05 (2017) |
| Druh dokumentu: | article |
| ISSN: | 0973-709X 2249-782X |
| DOI: | 10.7860/JCDR/2017/30115.10692 |
| Popis: | Introduction: The prevalence of Head and Neck Cancers (HNC) is very high in the Indian subcontinent. Radiotherapy is an essential modality in the management of HNC. Aim: The aim of the present study was to compare toxicities of two radiotherapy fractionation regimen (conventional fractionation and concomitant boost technique) for the management of HNC. Materials and Methods: A total of 60 patients (n=30 in each arm) were assigned to receive either conventional fractionation or concomitant boost radiotherapy. Toxicities were analysed weekly during the treatment, and one and three month after treatment completion. The radiation therapy oncology group acute radiation morbidity scoring system was used to document the severity. Toxicities assessed were mucositis, skin reactions, dysphagia and xerostomia. Statistical analysis was done by the online Graphpad software using Chi-square test. A value of p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|