Presentation of two patients with malignant granulosa cell tumors, with a review of the literature

Autor: Tamura Ryousuke, Yokoyama Yoshihito, Yanagita Takeshi, Matsumura Yukiko, Abe Kazuhiro, Taniguchi Ryousuke, Mizunuma Hideki
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: World Journal of Surgical Oncology, Vol 10, Iss 1, p 185 (2012)
Druh dokumentu: article
ISSN: 1477-7819
DOI: 10.1186/1477-7819-10-185
Popis: Abstract Granulosa cell tumors (GCTs) of the ovary account for 2 to 5 of ovarian malignancies. We present two patients with malignant ovarian adult GCT. In one patient, a combination of bleomycin, etoposide, and cisplatin was effective after initial surgery for malignant GCT. In the other, an aromatase inhibitor was effective for recurrent malignant GCT. We also review the literature for further management of this tumor. Because GCT of the ovary is rare, it will be necessary to elucidate the clinical phenotype and establish treatment protocols by accumulating and analyzing more patients.
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