Allergic bronchopulmonary mycosis caused by Scedosporium apiospermum: A case report

Autor: Ryota Okazaki, Shino Arita, Hinako Hoshio, Naoki Uetani, Genki Inui, Hiroki Ishikawa, Takafumi Nonaka, Hiroki Kohno, Yoshihiro Funaki, Tomoya Harada, Masato Morita, Akira Watanabe, Akira Yamasaki
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 51, Iss , Pp 102092- (2024)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2024.102092
Popis: A 61-year-old woman, hospitalized for a persistent cough and dyspnea, had no history of bronchial asthma, but was undergoing chemotherapy for methotrexate-related lymphoproliferative disorder due to rheumatoid arthritis. Her peripheral blood eosinophil count was significantly increased, and chest CT revealed left lower lobe atelectasis and high-attenuation mucus. Bronchoscopy revealed mucous plugs and pathological examination revealed numerous eosinophils and filamentous fungi. Allergic bronchopulmonary mycosis (ABPM) caused by Scedosporium apiospermum was diagnosed using culture and genetic analyses. Treatment with corticosteroids and antifungal drugs led to improvement. ABPM caused by S. apiospermum is extremely rare, emphasizing the importance of species identification.
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