STUDY OF THE EFFECT OF STRUCTURE ON OCTANOL-WATER DISTRIBUTION OF 6-HYDROXYPYRIMIDINE-4-(3H)-ONES DERIVATIVES

Autor:	A. E. Potapova, A. A. Teslev
Jazyk:	ruština
Rok vydání:	2019
Předmět:	pharmaceutical substance 6-hydroxypyrimidine-4(3h)-on partition coefficient absorption biopharmacy heterocyclic compounds ph lipophilicity Pharmaceutical industry HD9665-9675
Zdroj:	Разработка и регистрация лекарственных средств, Vol 0, Iss 2, Pp 170-174 (2019)
Druh dokumentu:	article
ISSN:	2305-2066 2658-5049
Popis:	The results of an experimental study of the effect of structure of substituting groups and pH value on the partition coefficients in biphasic systems of n-octanol and water for a number of 2,5-substituted 6-hydroxypyrimidine-4-(3H)-ones are presented.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/caa4709cfc67464cb10ca3669aee6ac9 Zobrazit plný text záznamu View record in DOAJ