MAVS is energized by Mff which senses mitochondrial metabolism via AMPK for acute antiviral immunity
Autor: | Yuki Hanada, Naotada Ishihara, Lixiang Wang, Hidenori Otera, Takaya Ishihara, Takumi Koshiba, Katsuyoshi Mihara, Yoshihiro Ogawa, Masatoshi Nomura |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
Druh dokumentu: | article |
ISSN: | 2041-1723 |
DOI: | 10.1038/s41467-020-19287-7 |
Popis: | Mitochondrial antiviral signalling protein (MAVS) is an adaptor of RIG-I like receptor. Here the authors show that mitochondrial fission factor (Mff) is required for clustering of MAVS on the outer mitochondrial membrane during antiviral response. |
Databáze: | Directory of Open Access Journals |
Externí odkaz: |
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