Sequential role of RAD51 paralog complexes in replication fork remodeling and restart
Autor: | Matteo Berti, Federico Teloni, Sofija Mijic, Sebastian Ursich, Jevgenij Fuchs, Maria Dilia Palumbieri, Jana Krietsch, Jonas A. Schmid, Edwige B. Garcin, Stéphanie Gon, Mauro Modesti, Matthias Altmeyer, Massimo Lopes |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
Druh dokumentu: | article |
ISSN: | 2041-1723 33346089 |
DOI: | 10.1038/s41467-020-17324-z |
Popis: | Replication stress has been associated with transient remodelling of replication intermediates into reversed forks, followed by efficient fork restart. Here the authors systematically analyse the role of RAD51 paralogs in these transactions, providing insights on the mechanistic role of different complexes of these proteins. |
Databáze: | Directory of Open Access Journals |
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