Refractory depressive disorder as the first manifestation of adolescent Sjögren’s syndrome, successfully treated with rituximab

Autor: Amal El-Ouakhoumi, Hajar Joulal, Jaouad Yousfi, Laila Benjilali, Mouna Zahlane, Lamiaa Essaadouni
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: European Journal of Case Reports in Internal Medicine (2024)
Druh dokumentu: article
ISSN: 2284-2594
DOI: 10.12890/2024_004621
Popis: Background: The psychiatric manifestations of Sjögren’s syndrome are often overlooked despite their prevalence. They can be revelatory of the disease and include anxiety, depression, dementia and, rarely, psychosis. Case description: We report a case of 18-year-old female in whom a major depressive syndrome revealed primary Sjögren’s disease, with a favourable outcome after treatment with rituximab. Conclusion: The diagnostic of Sjögren’s syndrome should be considered in patients who present with unexplained and refractory neuropsychiatric symptoms, even in the absence of sicca symptoms.
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