Autor: |
Michael S. Balzer, Tomohito Doke, Ya-Wen Yang, Daniel L. Aldridge, Hailong Hu, Hung Mai, Dhanunjay Mukhi, Ziyuan Ma, Rojesh Shrestha, Matthew B. Palmer, Christopher A. Hunter, Katalin Susztak |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-022-31772-9 |
Popis: |
After acute injury, kidneys either successfully repair/regenerate or become fibrotic. Here the authors use scRNA-seq to study adaptive/maladaptive kidney regeneration and identify proinflammatory/fibrotic proximal tubule cells with pharmacologically targetable pyroptosis/ferroptosis signatures. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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