Comorbidities of chronic rhinosinusitis in children and adults

Autor: Aada Murtomäki, Alma Helevä, Paulus Torkki, Jari Haukka, Anna Julkunen‐Iivari, Riikka Lemmetyinen, Mika Mäkelä, Aarno Dietz, Mikko Nuutinen, Sanna Toppila‐Salmi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical and Translational Allergy, Vol 14, Iss 4, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2045-7022
DOI: 10.1002/clt2.12354
Popis: Abstract Background Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the nose and paranasal sinuses lasting ≥12 weeks. CRS may exist with (CRSwNP) or without (CRSsNP) nasal polyps. The aim was to evaluate conditions associated with CRS in a randomized hospital cohort. We hypothesized that comorbidities and surgical procedures differ between pediatric and adult patients. Methods This study consisted of hospital registry data of a random sample of rhinosinusitis patients (age range 0–89 years) with the diagnosis of J32 or J33, correspondingly, registered during outpatient visits from 2005 to 2019 (n = 1461). The covariates of interest were collected from electronic health records based on ICD‐10 codes and keyword searches. Results Among pediatric patients (n = 104), the relative proportions of CRSsNP and CRSwNP were 86% and 14% respectively. The relative proportions of adult patients (n = 1357) with CRSsNP and CRSwNP were 60% and 40%, respectively. The following comorbidities significantly differed (p
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