| Autor: |
Mohamed Mamdouh Elsayed, Iman Ezzat Elgohary, Heidi Hesham Said Abdelhamid, Sherif Aziz Zaki |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMC Nephrology, Vol 24, Iss 1, Pp 1-8 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2369 |
| DOI: |
10.1186/s12882-023-03212-3 |
| Popis: |
Abstract Introduction Uremic pruritus (UP) is a common and distressing symptom in end stage renal disease (ESRD) patients. Many approaches have been tested to improve UP without a clear success. We aimed to assess the effect of sertraline on UP in hemodialysis (HD) patients. Methods This research is a double-blinded, placebo-controlled, multicentric randomized clinical trial which included sixty patients maintained on regular HD. Patients were allocated to receive sertraline 50 mg twice daily or placebo for 8 weeks. The Visual analogue scale (VAS) and the 5-D itch scale were used to assess pruritus before and after the course of treatment. Results At study end in sertraline group, there was a significant decrease from baseline findings in the VAS score (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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