| Autor: |
Ibrahim El‐Battrawy, Jonathan Demmer, Mohammad Abumayyaleh, Carina Crack, Christina Pilsinger, Xiaobo Zhou, Andreas Mügge, Ibrahim Akin, Assem Aweimer |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
ESC Heart Failure, Vol 10, Iss 2, Pp 943-954 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2055-5822 |
| DOI: |
10.1002/ehf2.14239 |
| Popis: |
Abstract Background Guidelines classify sacubitril/valsartan as a significant part of medical treatment of heart failure with reduced ejection fraction (HFrEF). Data have shown that the HbA1c levels in patients with diabetes mellitus could be impacted by sacubitril/valsartan. A possible positive effect in diabetes patients treated with sacubitril/valsartan on outcome and echocardiography parameters is not well studied yet. Aims The aim of the present study was to compare the impact of sacubitril/valsartan on life‐threatening arrhythmias, atrial fibrillation, different echocardiography parameters and congestion rate in patients suffering from HFrEF according to the diagnosis diabetes mellitus or no diabetes mellitus. Methods and results Consecutive 240 patients with HFrEF from 2016 to 2020 were treated with sacubitril/valsartan and separated to concomitant diabetes mellitus (n = 87, median age 68 years interquartile range (IQR) [32–87]) or no diabetes mellitus (n = 153, median age 66 year IQR [34–89]). Different comorbidities and outcome data were evaluated over a follow‐up period of 24 months. Arterial hypertension (87% vs. 64%; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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