| Autor: |
Lanbo Yang, BA, Mary Catherine Cambou, MD, Eddy R. Segura, MD, MPH, Marineide Gonçalves de Melo, MD, PhD, Breno Riegel Santos, MD, Ivana Rosângela dos Santos Varella, MD, PhD, Karin Nielsen-Saines, MD, MPH |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
AJOG Global Reports, Vol 3, Iss 2, Pp 100194- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2666-5778 |
| DOI: |
10.1016/j.xagr.2023.100194 |
| Popis: |
BACKGROUND: Childbirth via cesarean delivery can prevent intrapartum vertical transmission for women who are not virally suppressed at the time of delivery. Few studies have compared cesarean delivery trends between women living with HIV and women without HIV and have examined the role of cesarean delivery in the prevention of vertical transmission in the era of potent combination antiretroviral therapy. OBJECTIVE: We hypothesized that the cesarean delivery rate is high in women living with HIV compared with women without HIV and that cesarean delivery usage decreases over time among women living with HIV with advances in combined antiretroviral therapy in a country with a high national cesarean delivery rate. This study aimed (1) to evaluate cesarean delivery trends in women with and without HIV and (2) to examine its role in preventing vertical transmission among women living with HIV in a setting of free, universal combined antiretroviral therapy coverage in a retrospective cohort of nearly 56,000 deliveries at a major referral institution in a city with the highest prevalence of maternal HIV in Brazil. STUDY DESIGN: Data from maternal-infant pairs from January 1, 2008, to December 31, 2018, were extracted. Cesarean delivery rates were compared using the Pearson chi-square test. Cesarean delivery predictors were evaluated by multivariate log-linear Poisson regression using a generalized estimating equations approach. HIV viral suppression was defined as a viral load of |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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