Assessment of risk of obstructive sleep apnea with thyroid eye disease and its activity

Autor: Namita Kumari, Nitish Arora, Sima Das, Sweety Tiple, Harshdeep Singh, Narendra Patidar, Mihir Mishra, Atanu Majumdar
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Indian Journal of Ophthalmology, Vol 71, Iss 12, Pp 3711-3714 (2023)
Druh dokumentu: article
ISSN: 0301-4738
1998-3689
DOI: 10.4103/IJO.IJO_912_23
Popis: Purpose: To evaluate the association between obstructive sleep apnea (OSA) and thyroid eye disease (TED) and its effect on disease activity. Methods: A prospective case–control study was conducted from January 2020 to March 2022. All TED patients (group A) were clinically evaluated. The activity of thyroid eye disease was calculated based on the clinical activity score (CAS), and grading of severity was done according to the EUGOGO classification. All TED patients (group A) were screened for OSA using the Snoring Tired Observed Pressure (STOP)-Bang survey. Age- and gender-matched control group patients (group B) without TED were screened for OSA. Results: One hundred TED patients and 138 control patients without TED were included in the respective groups. Sixty-two (62%) patients in group A and 48 (34.78%) patients in group B were having high risk of OSA, and this difference was statistically significant (P = 0.001). Further, in group A patients, on univariate analysis, TED activity was significantly associated with a high risk of OSA (P = 0.009). On multivariate logistic regression analysis, OSA also showed significant association with TED activity (odds ratio [OR]: 4.14, 95% confidence interval [CI]: 1.11-18.85 at 10% level; P = 0.05). Conclusion: Our study showed that OSA is significantly associated with TED disease and its activity. However, no significant association was found between OSA and severity of the disease.
Databáze: Directory of Open Access Journals
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