Analysis of Titania Nanosheet Adsorption Behavior Using a Quartz Crystal Microbalance Sensor

Autor: Yuichiro Tashiro, Satoshi Komasa, Akiko Miyake, Hiroshi Nishizaki, Joji Okazaki
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Advances in Materials Science and Engineering, Vol 2018 (2018)
Druh dokumentu: article
ISSN: 1687-8434
1687-8442
DOI: 10.1155/2018/7461245
Popis: We investigated the adsorption of albumin and fibronectin on a titania nanosheet- (TNS-) modified quartz crystal microbalance (QCM) sensor. A Ti QCM sensor was fabricated by reactive magnetron sputtering. A thin layer of Ti was deposited on the QCM sensor. This sensor was then alkali-modified by treatment with NaOH at room temperature to fabricate the titania nanosheets. Scanning probe microscopy, X-ray photoelectron spectroscopy, and scanning electron microscopy were performed to investigate the surface topology and chemical components of each sensor. The TNS had a titanium oxide film exhibiting a nodular structure and a thickness of 13 nm on the QCM sensor. Furthermore, QCM measurements showed significantly greater amounts of albumin and fibronectin adsorbed on the TNS than on titanium. The NaOH treatment of titanium modified the sensor surface and improved the adsorption behaviors of proteins related to the initial adhesion of bone marrow cells. Therefore, we concluded that TNS improves the initial adhesion between the implant materials and the surrounding tissues.
Databáze: Directory of Open Access Journals
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