Premature mortality for patients after completely resected early adenocarcinoma of the esophagus or stomach

Autor: Elfriede Bollschweiler, Arnulf H. Hölscher, Sheraz R. Markar, Hakan Alakus, Uta Drebber, Stefan Paul Mönig, Patrick Sven Plum
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Cancer Medicine, Vol 13, Iss 10, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2045-7634
DOI: 10.1002/cam4.7223
Popis: Abstract Objective To establish the life expectancy burden of esophago‐gastric cancer by analyzing years of life lost (YLL) for a Western patient population after treatment of early esophageal (EAC) or early gastric (GAC) adenocarcinoma. Background For patients with early EAC or GAC, the short‐term prognosis after surgical resection is very good. Little data is available regarding long‐term prognosis when compared to the general population. Methods Two hundred and fourteen patients with pT1 EAC (n = 112) or GAC (n = 102) were included in the study. Patients with EAC underwent transthoracic en‐bloc esophagectomy; those with GAC had total or subtotal gastrectomy with D2‐lymphadenectomy. Surviving patients had a median follow‐up of approximately 14 years. YLL was calculated using average life expectancy data from Germany. Results Patients with EAC were younger (median age 61 years) than those with GAC (66 years) (p = 0.031). The male:female ratio was 10:1 for EAC and 3:2 for GAC (p
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