Mortality and cardiovascular and respiratory morbidity in individuals with impaired FEV1 (PURE): an international, community-based cohort study

Autor: MyLinh Duong, MBBS, Shofiqul Islam, PhD, Sumathy Rangarajan, MSc, Darryl Leong, PhD, Om Kurmi, PhD, Koon Teo, ProfMB, Kieran Killian, PhD, Gilles Dagenais, ProfMD, Scott Lear, ProfPhD, Andreas Wielgosz, ProfMD, Sanjeev Nair, ProfMD, Viswanathan Mohan, MD, Prem Mony, MD, Rajeev Gupta, ProfMD, Rajesh Kumar, ProfMD, Omar Rahman, ProfDSc, Khalid Yusoff, ProfMBBS, Johannes Lodewykus du Plessis, ProfPhD, Ehimario U Igumbor, PhD, Jephat Chifamba, DPhil, Wei Li, ProfPhD, Yin Lu, PhD, Fumin Zhi, BSc, Ruohua Yan, MSc, Romaina Iqbal, PhD, Noorhassim Ismail, ProfMD, Katarzyna Zatonska, MD, Kubilay Karsidag, ProfMD, Annika Rosengren, ProfMD, Ahmad Bahonar, MD, Afazalhussein Yusufali, MD, Pablo M Lamelas, MD, Alvaro Avezum, ProfMD, Patricio Lopez-Jaramillo, ProfMD, Fernando Lanas, ProfMD, Paul M O'Byrne, ProfMB, Salim Yusuf, ProfDPhil
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: The Lancet Global Health, Vol 7, Iss 5, Pp e613-e623 (2019)
Druh dokumentu: article
ISSN: 2214-109X
DOI: 10.1016/S2214-109X(19)30070-1
Popis: Summary: Background: The associations between the extent of forced expiratory volume in 1 s (FEV1) impairment and mortality, incident cardiovascular disease, and respiratory hospitalisations are unclear, and how these associations might vary across populations is unknown. Methods: In this international, community-based cohort study, we prospectively enrolled adults aged 35–70 years who had no intention of moving residences for 4 years from rural and urban communities across 17 countries. A portable spirometer was used to assess FEV1. FEV1 values were standardised within countries for height, age, and sex, and expressed as a percentage of the country-specific predicted FEV1 value (FEV1%). FEV1% was categorised as no impairment (FEV1% ≥0 SD from country-specific mean), mild impairment (FEV1%
Databáze: Directory of Open Access Journals