| Autor: |
Minerva Codruta Badescu, Oana Viola Badulescu, Liliana Gheorghe, Lăcrămioara Ionela Butnariu, Anca Ouatu, Diana Popescu, Oana Nicoleta Buliga-Finiș, Eusebiu Vlad Gorduza, Manuela Ciocoiu, Ciprian Rezus |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Life, Vol 14, Iss 3, p 354 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2075-1729 |
| DOI: |
10.3390/life14030354 |
| Popis: |
Hemophiliacs can develop cardiovascular diseases, including valvulopathies of various etiologies and severities. Some require surgical treatment. Performing cardiac surgery in hemophiliacs is a challenge because they maintain an increased risk of bleeding throughout their lives. Our review shows that with a multidisciplinary team and careful planning, cardiac surgery can be safely performed in these patients. Valve repair and bioprosthetic valves should be preferred over mechanical valves to avoid life-long anticoagulation. In patients who cannot receive a bioprosthetic valve, the use of the On-X mechanical valve might be considered because it requires less intensive anticoagulation after 3 months of treatment. Antithrombotic treatment is feasible in hemophiliacs only if the coagulation factor level is kept constantly above a specific trough limit. Our review is valuable because, for the first time, the available data on the modern surgical treatment of valvular disease in hemophiliacs have been synthesized and systematized. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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