Diagnosis of bacteraemia and growth times

Autor: Jose Manuel Ruiz-Giardín, Rosa M. Martin-Díaz, Jerónimo Jaqueti-Aroca, Isabel Garcia-Arata, Juan Víctor San Martín-López, Miguel Sáiz-Sánchez Buitrago
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 41, Iss C, Pp 6-10 (2015)
Druh dokumentu: article
ISSN: 1201-9712
1878-3511
DOI: 10.1016/j.ijid.2015.10.008
Popis: Objective: The objective of this study was to predict the diagnosis of bacteraemia as a function of the time at which the automated BacT/Alert system continuously detects microorganism growth. Methods: A retrospective study of a database of 1334 patients with a positive blood culture between January 2011 and June 2013 was conducted. Together with the final blood culture results and the patient's history, growth was then analysed to assess whether it represented true bacteraemia or bacterial contamination. The earliest detection times of bacterial growth in each batch of blood cultures were analysed in a blinded fashion after classification. Results: In total, 590 batches of blood cultures corresponded to true bacteraemia and 744 to bacterial contamination. In the bacteraemia group, the median growth time was 12.72 h (interquartile range (IQR) 10.08–17.58 h). In the contaminated blood culture group, the median growth time was 20.6 h (IQR 17.04–32.16 h) (p
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