The Pathophysiological Rationale for Personalized Metabolic Therapy of ASD. Promising Treatments

Autor: S.I. Polyakova
Jazyk: ruština
Rok vydání: 2019
Předmět:
Zdroj: Аутизм и нарушение развития, Vol 17, Iss 1, Pp 55-70 (2019)
Druh dokumentu: article
ISSN: 1994-1617
2413-4317
DOI: 10.17759/autdd.2019170106
Popis: A metabolic disorder is a serious problem. Changes that occur at the cellular level and are associated with biochemical processes lead to malfunctioning of the cell, and further, respectively, of tissue, organ, of the whole organism. Metabolic care is the basis of metabolic therapy. For almost every metabolic regimen of autism spectrum disorder, there is a counter-argument. For this reason, a unified approach to therapy is impossible, since, apart from the “autistic triad”, each person has his own peculiarities. At the present stage, in addition to a gluten-free and casein-free diet, vitamins of groups B and D, polyunsaturated fatty acids, various methods of microbiome correction are used in therapy, but there is no serious evidence base for the effectiveness of therapy for autism spectrum disorders. The article proposes options for the study of metabolic changes in the body, which are the rationale for the development of a scheme of metabolic therapy in the framework of a personalized medical approach to the treatment of autism spectrum disorders.
Databáze: Directory of Open Access Journals