Unlocking the efficiency of genomics laboratories with robotic liquid-handling

Autor: Houriiyah Tegally, James Emmanuel San, Jennifer Giandhari, Tulio de Oliveira
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Genomics, Vol 21, Iss 1, Pp 1-15 (2020)
Druh dokumentu: article
ISSN: 1471-2164
DOI: 10.1186/s12864-020-07137-1
Popis: Abstract In research and clinical genomics laboratories today, sample preparation is the bottleneck of experiments, particularly when it comes to high-throughput next generation sequencing (NGS). More genomics laboratories are now considering liquid-handling automation to make the sequencing workflow more efficient and cost effective. The question remains as to its suitability and return on investment. A number of points need to be carefully considered before introducing robots into biological laboratories. Here, we describe the state-of-the-art technology of both sophisticated and do-it-yourself (DIY) robotic liquid-handlers and provide a practical review of the motivation, implications and requirements of laboratory automation for genome sequencing experiments.
Databáze: Directory of Open Access Journals
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