Study on the total proteins and main protein fractions in rabbits experimentally infected with Staphylococcus aureus
| Autor: | T. M. Georgieva, V. Petrov, Iv. P. Georgiev, N. Nikolova, M. Lyutskanov, N. Bozakova |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Trakia Journal of Sciences, Vol 15, Iss 1, Pp 42-49 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1312-1723 1313-3551 |
| DOI: | 10.15547/tjs.2017.01.007 |
| Popis: | Infections with Staphylococcus aureus are a common cause which can induce severe skin infections in rabbits leading to important economic losses. The present study was conducted to evaluate the changes in the concentrations of total protein, albumin, globulin, fibrinogen, and albumin/globulin ratio during S. aureus infection using a model for experimental infection of rabbits. The experiment was carried out on 13 rabbits at the age of 3 months. Infection was induced by inoculation of 7 rabbits by100 μL of bacterial suspension of a field S. aureus strain (density: 8х108 cfu/mL) and 6 other rabbits were not treated (controls). Blood samples for principal protein analysis were collected before (0 h) and at 24, 48 and72 h on day 7, 14, and 21 after infection. Total protein level showed little changes in the experimental group. The concentration of albumin decreased in the experimental group since 32.2±2.30 g/L to 27.3±1.9g/L. The serum level of globulins rose significantly (P |
| Databáze: | Directory of Open Access Journals |
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