Association between metabolic syndrome and lupus nephritis activity
| Autor: | Rabrenović Violeta, Petrović Milica, Rabrenović Milorad, Rančić Nemanja |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Medical Biochemistry, Vol 43, Iss 4, Pp 565-573 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1452-8258 1452-8266 |
| DOI: | 10.5937/jomb0-45732 |
| Popis: | Background: Metabolic syndrome (MetS) in patients with systemic lupus erythematosus (SLE) represents an additional burden and a poor prognostic factor for the onset or worsening of atherosclerosis and cardiovascular complications. In many patients with lupus nephritis (LN), MetS is often already manifested initially. Our work aimed to determine the frequency and characteristics of MetS in patients with LN, as well as the relationship components of MetS and characteristics of disease activity. Methods: The clinical study included 67 patients with LN, 54 (80.59%) female and 13 (19.41%) male, with an average age of 42.86±14.46 years. Patients were divided into two groups: with MetS (35.82%) and without MetS (64.18%), active LN had (34 or 50.74%), and LN in remission (33 or 49.25%). We monitored clinical and biochemical parameters of interest. Results: Comparing patients with LN collectively, as well as those with MetS and without MetS, we observed that patients with MetS were older (p=0.001), BMI (p |
| Databáze: | Directory of Open Access Journals |
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