Low-dose warfarin in high-risk pregnant patients with mechanical valves: A randomized clinical trial

Autor: Ahmed Hassouna, Ayman Ammar, Yasser Elnahas, Ahmed Toema, Hemat Allam
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: The Egyptian Heart Journal, Vol 66, Iss 1, p 14 (2014)
Druh dokumentu: article
ISSN: 1110-2608
DOI: 10.1016/j.ehj.2013.12.039
Popis: Low-dose Warfarin (LDW) throughout pregnancy was suggested to provide safe and effective anticoagulation in pregnant patients with mechanical heart valve prosthesis (MHVP). We aimed to study its rate of failure in achieving target INR of those patients. Methods: Group A: 100 pregnant patients with mitral (+aortic; 24%) MHVP were randomized in a 3:1 ratio, to either receive LDW (
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