A Study to Assess the Role of Psychological Stress in the Severity of Oral Lichen Planus, OSMF, and Leukoplakia and its Correlation with Serum Cortisol Levels
| Autor: | Saba Khan, Dhaval N. Mehta, Pooja Jain, Saurabh Somani, Mohammed A. Pathan, Helly Thakkar, Swati Agrawal |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss Suppl 3, Pp S2021-S2023 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0976-4879 0975-7406 |
| DOI: | 10.4103/jpbs.jpbs_1267_23 |
| Popis: | Introduction: The most prevalent oral mucosal conditions in humans are leukoplakia, oral lichen planus (OLP), and oral submucous fibrosis (OSMF). These conditions should be studied as psychosomatic conditions, but little research has been done on how these conditions relate to stress. Materials and Methods: A total of 280 patients of both genders with ages 35–60 years were divided into four groups: leukoplakia, OSMF, OLP, and control. Whole blood samples were collected from all the participants and analyzed for serum cortisol by using ELISA with a commercial kit. Detailed case history and DASS-21 questionnaire were recorded for psychological assessment. To assess the variables, the student t test and Chi-square test were used. P values of |
| Databáze: | Directory of Open Access Journals |
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