Effect of low vs. high vancomycin trough level on the clinical outcomes of adult patients with sepsis or gram-positive bacterial infections: a systematic review and meta-analysis

Autor: Subhash Chander, Roopa Kumari, Hong Yu Wang, Yaqub Nadeem Mohammed, Om Parkash, Sindhu Lohana, FNU Sorath, Abhi Chand Lohana, FNU Sadarat, Sheena Shiwlani
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-16 (2024)
Druh dokumentu: article
ISSN: 1471-2334
DOI: 10.1186/s12879-024-09927-4
Popis: Abstract Background & objective The Infectious Disease Society of America guidelines recommend vancomycin trough levels of 15–20 mg/L for severe methicillin-resistant Staphylococcus aureus. However, recent consensus guidelines of four infectious disease organizations no longer recommend vancomycin dosing using minimum serum trough concentrations. Therefore, this study aimed to evaluate the impact of low (
Databáze: Directory of Open Access Journals
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