Autor: |
P Kanda, M A Wells |
Jazyk: |
angličtina |
Rok vydání: |
1981 |
Předmět: |
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Zdroj: |
Journal of Lipid Research, Vol 22, Iss 5, Pp 877-879 (1981) |
Druh dokumentu: |
article |
ISSN: |
0022-2275 |
DOI: |
10.1016/S0022-2275(20)37361-2 |
Popis: |
A simplified procedure for the synthesis of short acyl chain phosphatidylcholines is described. A mixed fatty acid-trifluoroacetic anhydride is used to acylate sn-glycero-3-phosphocholine (GPC) which has been dissolved in trifluoroacetic acid. Yields exceeding 70% are achieved in 30-min reaction time using 1.5 to 2.0 equivalents of mixed anhydride per, GPC hydroxyl. This allows a more economical use of labeled short chain acids. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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