Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS‐CoV‐2 Omicron strain infection in China: A national multicenter survey of 35,566 individuals

Autor: Meng‐Fan Liu, Rui‐Xia Ma, Xian‐Bao Cao, Hua Zhang, Shui‐Hong Zhou, Wei‐Hong Jiang, Yan Jiang, Jing‐Wu Sun, Qin‐Tai Yang, Xue‐Zhong Li, Ya‐Nan Sun, Li Shi, Min Wang, Xi‐Cheng Song, Fu‐Quan Chen, Xiao‐Shu Zhang, Hong‐Quan Wei, Shao‐Qing Yu, Dong‐Dong Zhu, Luo Ba, Zhi‐Wei Cao, Xu‐Ping Xiao, Xin Wei, Zhi‐Hong Lin, Feng‐Hong Chen, Chun‐Guang Shan, Guang‐Ke Wang, Jing Ye, Shen‐Hong Qu, Chang‐Qing Zhao, Zhen‐Lin Wang, Hua‐Bin Li, Feng Liu, Xiao‐Bo Cui, Sheng‐Nan Ye, Zheng Liu, Yu Xu, Xiao Cai, Wei Huang, Ru‐Xin Zhang, Yu‐Lin Zhao, Guo‐Dong Yu, Guang‐Gang Shi, Mei‐Ping Lu, Yang Shen, Yu‐Tong Zhao, Jia‐Hong Pei, Shao‐Bing Xie, Long‐Gang Yu, Ye‐Hai Liu, Shao‐Wei Gu, Yu‐Cheng Yang, Lei Cheng, Jian‐Feng liu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: World Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 10, Iss 2, Pp 113-120 (2024)
Druh dokumentu: article
ISSN: 2589-1081
2095-8811
DOI: 10.1002/wjo2.167
Popis: Abstract Objective This cross‐sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID‐19 in China. Methods This study was conducted by 45 tertiary Grade‐A hospitals in China. Online and offline questionnaire data were obtained from patients infected with COVID‐19 between December 28, 2022, and February 21, 2023. The collected information included basic demographics, medical history, smoking and drinking history, vaccination history, changes in olfactory and gustatory functions before and after infection, and other postinfection symptoms, as well as the duration and improvement status of olfactory and gustatory disorders. Results Complete questionnaires were obtained from 35,566 subjects. The overall incidence of olfactory and taste dysfunction was 67.75%. Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste dysfunction. Having received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such dysfunction. Before infection, the average olfactory and taste VAS scores were 8.41 and 8.51, respectively; after infection, they decreased to 3.69 and 4.29 and recovered to 5.83 and 6.55 by the time of the survey. The median duration of dysosmia and dysgeusia was 15 and 12 days, respectively, with 0.5% of patients having symptoms lasting for more than 28 days. The overall self‐reported improvement rate was 59.16%. Recovery was higher in males, never smokers, those who received two or three vaccine doses, and those that had never experienced dental health issues, or chronic accompanying symptoms. Conclusions The incidence of dysosmia and dysgeusia following infection with the SARS‐CoV‐2 virus is high in China. Incidence and prognosis are influenced by several factors, including sex, SARS‐CoV‐2 vaccination, history of head‐facial trauma, nasal and oral health status, smoking and drinking history, and the persistence of accompanying symptoms.
Databáze: Directory of Open Access Journals
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