Distinction of IgG4-related mastitis from breast cancer: a case report

Autor: Banri Tsuda, Nobue Kumaki, Rie Ishida, Mari Mizuno, Kozue Yokoyama, Risa Oshitanai, Mayako Terao, Toru Morioka, Takuho Okamura, Yuki Saito, Yasuhiro Suzuki, Naoki Niikura
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Surgical Case Reports, Vol 5, Iss 1, Pp 1-5 (2019)
Druh dokumentu: article
ISSN: 2198-7793
DOI: 10.1186/s40792-019-0681-y
Popis: Abstract Background Immunoglobulin (Ig) G4-related sclerosing disease is a pathological concept proposed in Japan during the early 2000s. This lesion-forming disease may exhibit characteristics of a systemic disease but often affects a single organ. To date, IgG4-related sclerosing disease in the mammary gland, or IgG4-related mastitis (IgG4-RM), has rarely been reported. Case presentation Here, we describe the case of a female patient who was admitted to our hospital with the main complaints of left breast and axillary lymphadenopathy. A careful diagnostic imaging examination led to an initial suspicion of breast cancer. However, a needle biopsy led to a diagnosis of IgG4-RM. Subsequently, the patient was successfully treated with predonin. Conclusions The treatment requirements for breast cancer and IgG4-RM differ considerably. This is a good example of a case wherein unnecessary surgical treatment, which is indicated for breast cancer, was avoided by needle biopsy. Accordingly, the patient was appropriately treated with steroids following a correct diagnosis.
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