Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment

Autor: N. MacKinnon, M. Alinaghian, P. Silva, T. Gloge, B. Luy, M. Jouda, J. G. Korvink
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Magnetic Resonance, Vol 2, Pp 835-842 (2021)
Druh dokumentu: article
ISSN: 2699-0016
DOI: 10.5194/mr-2-835-2021
Popis: Band selectivity to address specific resonances in a spectrum enables one to encode individual settings for diffusion experiments. In a single experiment, this could include different gradient strengths (enabling coverage of a larger range of diffusion constants), different diffusion delays, or different gradient directions (enabling anisotropic diffusion measurement). In this report, a selective variant of the bipolar pulsed gradient eddy current delay (BPP-LED) experiment, enabling selective encoding of three resonances, was implemented. As proof of principle, the diffusion encoding gradient amplitude was assigned a range dependent on the selected signal, thereby allowing the extraction of the diffusion coefficient for water and a tripeptide (Met-Ala-Ser) with optimal settings in a single experiment.
Databáze: Directory of Open Access Journals