Paroxetine in the Treatment of Post Traumatic Stress Disorder: Our Experiences

Autor: Abdulah Kučukalić, Alma Bravo-Mehmedbašić, Alma Džubur-Kulenović
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Biomolecules & Biomedicine, Vol 8, Iss 1 (2008)
Druh dokumentu: article
ISSN: 2831-0896
2831-090X
DOI: 10.17305/bjbms.2008.3002
Popis: Posttraumatic stress disorder can develop after individual’s exposure or witnessing of life threatening events. It is characterized by three clusters of symptoms. The course of PTSD is often chronic and impedes individual’s functioning. Studies of PTSD treatment with paroxetine provide evidence for its efficacy in reducing symptoms and its favorable profile of side-effects. The objective of this work was to determine the efficacy of paroxetine in the treatment of PTSD. The sample consisted of 30 subjects with chronic PTSD. All subjects received treatment with paroxetine in therapeutic dose range for six months. Subjects were assessed prior to therapy and following six months of treatment with paroxetine with the use of following instruments: SCL 90-R, Mississippi Questionnaire, and CGI. The results indicate statistically significant reduction on all subscales of SCL 90-R following six months of treatment, P
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