The Effects of Viral Infections on the Molecular and Signaling Pathways Involved in the Development of the PAOs

Autor: Xiaozhou Liu, Zhengdong Zhao, Xinyu Shi, Yanjun Zong, Yu Sun
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Viruses, Vol 16, Iss 8, p 1342 (2024)
Druh dokumentu: article
ISSN: 1999-4915
DOI: 10.3390/v16081342
Popis: Cytomegalovirus infection contributes to 10–30% of congenital hearing loss in children. Vertebrate peripheral auditory organs include the outer, middle, and inner ear. Their development is regulated by multiple signaling pathways. However, most ear diseases due to viral infections are due to congenital infections and reactivation and affect healthy adults to a lesser extent. This may be due to the fact that viral infections affect signaling pathways that are important for the development of peripheral hearing organs. Therefore, an in-depth understanding of the relationship between viral infections and the signaling pathways involved in the development of peripheral hearing organs is important for the prevention and treatment of ear diseases. In this review, we summarize the effects of viruses on signaling pathways and signaling molecules in the development of peripheral auditory organs.
Databáze: Directory of Open Access Journals
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