| Autor: |
Taneli Lehto, Teemu Zetterman, Ritva Markkula, Jari Arokoski, Heikki Tikkanen, Eija Kalso, Juha E. Peltonen |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-15 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2474 |
| DOI: |
10.1186/s12891-023-06589-2 |
| Popis: |
Abstract Background Patients with fibromyalgia (FM) exhibit low peak oxygen uptake ( $$\dot{\text{V}}$$ V ˙ O2peak). We aimed to detect the contribution of cardiac output to ( $$\dot{\text{Q}}$$ Q ˙ ) and arteriovenous oxygen difference $$[\text{C}(\text{a-v})\text{O}_{2}]$$ [ C ( a-v ) O 2 ] to $$\dot{\text{V}}\text{O}_{2}$$ V ˙ O 2 from rest to peak exercise in patients with FM. Methods Thirty-five women with FM, aged 23 to 65 years, and 23 healthy controls performed a step incremental cycle ergometer test until volitional fatigue. Alveolar gas exchange and pulmonary ventilation were measured breath-by-breath and adjusted for fat-free body mass (FFM) where appropriate. $$\dot{\text{Q}}$$ Q ˙ (impedance cardiography) was monitored. $$\text{C}(\text{a-v})\text{O}_{2}$$ C ( a-v ) O 2 was calculated using Fick’s equation. Linear regression slopes for oxygen cost (∆ $$\dot{\text{V}}$$ V ˙ O2/∆work rate) and $$\dot{\text{Q}}$$ Q ˙ to $$\text{V}$$ V O2 (∆ $$\dot{\text{Q}}$$ Q ˙ /∆ $$\dot{\text{V}}$$ V ˙ O2) were calculated. Normally distributed data were reported as mean ± SD and non-normal data as median [interquartile range]. Results $$\dot{\text{V}}$$ V ˙ O2peak was lower in FM patients than in controls (22.2 ± 5.1 vs. 31.1 ± 7.9 mL∙min−1∙kg−1, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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