Clinical role of increased apolipoprotein B levels in coronary heart disease

Autor: S. A. Pataraya, D. V. Preobrazhensky
Jazyk: ruština
Rok vydání: 1970
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 7, Iss 7, Pp 51-54 (1970)
Druh dokumentu: article
ISSN: 1728-8800
2619-0125
Popis: Aim. To investigate clinical role of serum apolipoprotein B (apo B) levels in coronary heart disease (CHD). Material and methods. The study included 122 patients (mean age 49,7±7,1 years) with possible CHD diagnosis, who underwent clinical and instrumental examination. The diagnosis was confirmed by anamnesis data, stress tests and coronary angiography results. Apo B concentration was measured by immune-enzyme method. Results. In women, sensitivity of elevated apo B levels was lower than that of hypercholesterolemia (HCH); nevertheless, specificity of both parameters was similar. In men, HCH was more sensitive and specific than increased apo B levels. Conclusion. Substantial differences in sensitivity and specificity of increased apo B levels were observed in women and men with possible CHD, as well as in various groups of men.
Databáze: Directory of Open Access Journals