Comparative analysis of the course and outcomes of a new coronavirus infection depending on the level of high-density lipoproteins in hospitalized patients with COVID-19

Autor: I. A. Frolova, E. I. Tarlovskaya, S. V. Romanov
Jazyk: ruština
Rok vydání: 2022
Předmět:
Zdroj: Атеросклероз, Vol 18, Iss 2, Pp 117-128 (2022)
Druh dokumentu: article
ISSN: 2078-256X
DOI: 10.52727/2078-256X-2022-18-2-117-128
Popis: Aim of the study was to analyze the course and outcomes of a new coronavirus infection depending on the level of high-density lipoproteins in hospitalized patients with COVID-19. Material and methods. A retrospective analysis of the medical histories of 208 patients hospitalized with a diagnosis of COVID-19 was carried out. Depending on the level of high-density lipoproteins (HDL), patients were divided into 2 groups: group 1 – patients with «low» HDL < 0.83 mmol/l, group 2 – patients with «high» HDL ≥ 0.83 mmol/l. The relationship between HDL levels measured at the beginning of hospitalization and the severity of the course and outcomes of coronavirus infection was evaluated. The primary endpoint was nosocomial death, secondary points: the development of complications of coronavirus infection, the duration of hospitalization, the duration of fever, the duration of stay in the intensive care unit (ICU). Results. In hospitalized patients with COVID-19, lipid profile disorders were observed in the form of a decrease in HDL (
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