A systematic review on the modifications of extracellular vesicles: a revolutionized tool of nano-biotechnology

Autor: Alok Raghav, Goo-Bo Jeong
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-19 (2021)
Druh dokumentu: article
ISSN: 1477-3155
DOI: 10.1186/s12951-021-01219-2
Popis: Highlights Extracellular vesicles (EVs) can be modified using various methods available including physical, chemical and engineering based. These tailoring methods are helpful in targeting drug delivery to treat various diseases. Moreover, EVs have the ability to modify that’s due to presence of lipid bilayer membrane, that’s effectively participate in loading and unloading of desired drug. EVs expressed from the specific cell types can give useful information about the pathogenesis of a particular disease in the form of unique nucleic acids, protein and lipid sequences and therefore, EVs derived from these cells can be used as specific diagnostic biomarker for diagnosis of diseases. Modified EVs using various drugs or miRNAs can be used for targeted drug delivery to specific cells.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje