Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies
| Autor: | А. S. Tertychnyy, Т. L. Lapina, D. Р. Nagornaya, N. V. Pachuashvili, А. Р. Kiryukhin, А. А. Fedorenko, Р. V. Pavlov, D. D. Protsenko, V. Т. Ivashkin |
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| Jazyk: | ruština |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 34, Iss 2, Pp 45-56 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1382-4376 2658-6673 |
| DOI: | 10.22416/1382-4376-2024-34-2-45-56 |
| Popis: | Aim: in the retrospective study to assess the frequency of various gastritis variants based on the results of morphological examination of gastric biopsies over a 5-year observation period.Methods. The study included 3162 individuals who underwent esophagogastroduodenoscopy with biopsy collection between 2017 and 2022. Pathological examination of biopsies was conducted using the updated Sydney system, determining the histological variant and, when possible, the etiology of gastritis. In some cases, chronic gastritis was assessed using the OLGA/OLGIM system.Results. The most frequently diagnosed type was active H. pylori-associated gastritis (36.7 %), followed by chronic atrophic gastritis with intestinal metaplasia in cases where H. pylori infection was not detected (28.4 %), including immunohistochemical examination, classified as gastritis after successful H. pylori eradication. Atrophic forms of chronic gastritis constituted 34.8 %. Minimal or mild changes close to normal histological characteristics were оbserved in 19.2 % of patients. Reactive gastropathy was present in 7.6 % of cases. Autoimmune gastritis ranked fourth in frequency, with a relatively high percentage of observations (8.6 %).Conclusion. According to the analysis of gastric biopsies in the Russian population, a high frequency of H. pylori-associated gastritis was observed, and autoimmune gastritis is not uncommon. The high prevalence of atrophic gastritis emphasizes the importance of dynamic patient monitoring within cancer prevention programs. |
| Databáze: | Directory of Open Access Journals |
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