Ventricular evoked response in patients with hypertrophic obstructive cardiomyopathy treated with DDD pacing

Autor: João Ricardo M. Sant'Anna, Raquel Prati, Helmut Hutten, Günter Schreier, Peter Kastner, Renato A. K. Kalil, Paulo R. Prates, Iran Castro, Paulo C. Azambuja, Farid Faes, Ivo A. Nesralla, Max Schaldach
Jazyk: English<br />Portuguese
Rok vydání: 1999
Předmět:
Zdroj: Arquivos Brasileiros de Cardiologia, Vol 73, Iss 2, Pp 169-179 (1999)
Druh dokumentu: article
ISSN: 0066-782X
1678-4170
DOI: 10.1590/S0066-782X1999000800005
Popis: OBJECTIVE: To assess the changes in ventricular evoked responses (VER) produced by the decrease in left ventricular outflow tract gradient (LVOTG) in patients with hypertrophic obstructive cardiomyopathy (HOCM) treated with dual-chamber (DDD) pacing. METHODS: A pulse generator Physios CTM (Biotronik, Germany) was implanted in 9 patients with severe drug-refractory HOCM. After implantation, the following conditions were assessed: 1) Baseline evaluation: different AV delay (ranging from 150ms to 50 ms) were sequentially programmed during 5 to 10 minutes, and the LVOTG (as determined by Doppler echocardiography) and VER recorded; 2) standard evaluation, when the best AV delay (resulting in the lowest LVOTG) programmed at the initial evaluation was maintained so that its effect on VER and LVOTG could be assessed during each chronic pacing evaluation. RESULTS: LVOTG decreased after DDD pacing, with a mean value of 59 ± 24 mmHg after dual chamber pacemaker, which was significantly less than the gradient before pacing (98 + 22mmHg). An AV delay >100ms produced a significantly lower decrease in VER depolarization duration (VER DD) when compared to an AV delay
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