Perspectives on skeletal muscle stem cells

Autor: F. Relaix, M. Bencze, M. J. Borok, A. Der Vartanian, F. Gattazzo, D. Mademtzoglou, S. Perez-Diaz, A. Prola, P. C. Reyes-Fernandez, A. Rotini, Taglietti
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-20760-6
Popis: Skeletal muscle has a remarkable regenerative capacity, which can largely be attributed to resident muscle stem cells (MuSCs). Here, the authors review the molecular mechanisms regulating MuSC quiescence, activation and proliferation, how these processes are regulated by the stem cell niche, and the role of MuSCs in neuromuscular diseases.
Databáze: Directory of Open Access Journals