Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review

Autor: Yik Long Man, Giovanni Sanna
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Brain Sciences, Vol 12, Iss 1, p 91 (2022)
Druh dokumentu: article
ISSN: 2076-3425
DOI: 10.3390/brainsci12010091
Popis: Antiphospholipid syndrome (APS) is a common autoimmune pro-thrombotic condition characterised by thrombosis and pregnancy morbidity. There are a broad range of neuropsychiatric manifestations associated with APS, from focal symptoms to more global dysfunction. Patients commonly present with transient ischaemic attacks and ischaemic strokes, with identifiable lesions on brain imaging. However, the underlying pathogenesis remains uncertain in other manifestations, such as cognitive dysfunction, seizures, headache and chorea. The aim is to provide a comprehensive review of the various neuropsychiatric manifestations associated with APS. A detailed literature search was applied to PubMed, including citations from 1983 to December 2021.
Databáze: Directory of Open Access Journals
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