NMR microscopy of tissue in organic and mixed solvents

Autor:	Macura Slobodan, Mishra Prasanna K., Gamez Jeffrey D., Pirko Istvan
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	NMR MRI MRM nuclear magnetic resonance NMR imaging NMR microscopy magnetization transfer cross-relaxation Chemistry QD1-999
Zdroj:	Journal of the Serbian Chemical Society, Vol 78, Iss 11, Pp 1641-1654 (2013)
Druh dokumentu:	article
ISSN:	0352-5139 1820-7421 13110810
DOI:	10.2298/JSC131108108M
Popis:	We propose to use organic and mixed solvents for nuclear magnetic resonance microscopy of fixed tissue as a means for improving image information content. NMR properties of some standard solvents (methanol, acetone, DMSO) and solvents in use for tissue processing in pathology (xylenes, paraffin, ‘Clearify’) have been measured, reviewed, and analyzed. It was found that DMSO and paraffin are very useful solvents that provide images of better quality than those obtained in water (neutralized formalin buffer). This is illustrated on the formalin fixed mouse brain sections imaged at 16.4 teslas (700 MHz).
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/4578e5aad7174637ad0c0952de2c7e73 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF