Empowering alcohols as carbonyl surrogates for Grignard-type reactions

Autor: Chen-Chen Li, Haining Wang, Malcolm M. Sim, Zihang Qiu, Zhang-Pei Chen, Rustam Z. Khaliullin, Chao-Jun Li
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-19857-9
Popis: Alcohols are more naturally abundant than carbonyl compounds, which in turn are well known for their reactivity in Grignard reactions. Here, the authors showcase a distinct Grignard-like reactivity by using alcohols as coupling partners with hydrazones and synthesize more complex alcohols under ruthenium catalysis.
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