| Autor: |
Christian Matthias Zobel, Werner Wenzel, Jan Philipp Krüger, Ulrich Baumgarten, Tobias Wagelöhner, Nino Neumann, Behruz Foroutan, Rico Müller, Annette Müller, Dominic Rauschning, Meike Schüßler, Lorenz Scheit, Felix Weinreich, Klaas Oltmanns, Franziska Keidel, Maria Koch, Sebastian Spethmann, Maximilian Schreiner |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Frontiers in Microbiology, Vol 14 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1664-302X |
| DOI: |
10.3389/fmicb.2023.1256210 |
| Popis: |
BackgroundCOVID-19 can show a variable course, from asymptomatic infections to acute respiratory failure and death. For efficient allocation of resources, patients should be stratified according to their risk for a severe course as early as possible.Methods135 hospitalized patients with COVID-19 pneumonia at four German hospitals were prospectively included in this observational study. A standardized clinical laboratory profile was taken at hospital admission and a panel of serum markers with possible roles in the COVID-associated cytokine storm were also determined. 112 patients could be evaluated. The primary endpoint of ventilator requirement or death within 30 days of symptom onset was met by 13 patients.ResultsSerum elevations of interleukin-6 (IL-6), procalcitonin (PCT), and C-reactive protein (CRP) at hospital admission were each highly significantly (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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