Comparison of a Rapid Multiplex Gastrointestinal Panel with Standard Laboratory Testing in the Management of Children with Hematochezia in a Pediatric Emergency Department: Randomized Controlled Trial

Autor: Jianling Xie, Kelly Kim, Byron M. Berenger, Linda Chui, Otto G. Vanderkooi, Silviu Grisaru, Stephen B. Freedman
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Microbiology Spectrum, Vol 11, Iss 3 (2023)
Druh dokumentu: article
ISSN: 2165-0497
DOI: 10.1128/spectrum.00268-23
Popis: ABSTRACT Advances in diagnostic microbiology allow for the rapid identification of a broad range of enteropathogens; such knowledge can inform care and reduce testing. We conducted a randomized, unblinded trial in a tertiary-care pediatric emergency department. Participants had stool (and rectal swabs if stool was not immediately available) tested using routine microbiologic approaches or by use of a device (BioFire FilmArray gastrointestinal panel), which identifies 22 pathogens with a 1-h instrument turnaround time. Participants were 6 months to
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