Long-chain noncoding RNA NEAT1 and autoimmune diseases

Autor: Cheng Bao, Li-Li Tian, Xiao-Liu Li, Min Xu, Hong-Wei Chen
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Exploration of Immunology, Vol 4, Iss 5, Pp 616-623 (2024)
Druh dokumentu: article
ISSN: 2768-6655
DOI: 10.37349/ei.2024.00162
Popis: Autoimmune diseases result from the immune system’s response to autoantigen components, leading to damage to one’s own tissues and organs. The correlation between long noncoding RNAs (lncRNAs) and autoimmune diseases remains inconclusive. However, recent studies have revealed that the lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1) plays a vital role in the development of various autoimmune diseases. Here, this review briefly summarizes the progress in understanding NEAT1 expression variations and related mechanisms in different autoimmune diseases, and discusses its potential use for future therapeutic applications.
Databáze: Directory of Open Access Journals