Prostate ductal adenocarcinoma exhibiting a late recurrence in the anterior urethra 13 years post-total prostatectomy: a case report

Autor: Seiichiro Honda, Takashi Kawahara, Reiko Tanaka, Shu Yuguchi, Shoji Yamanaka, Satoshi Fujii, Akihito Hasizume, Kimito Osaka, Noboru Mimura, Jurii Karibe, Takeaki Noguchi, Kota Shimokihara, Daiji Takamoto, Teppei Takeshima, Jun-ichi Teranishi, Kazuhide Makiyama, Hiroji Uemura
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-5 (2024)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.1186/s13256-024-04699-6
Popis: Abstract Background Prostate ductal adenocarcinoma, a rare histology observed in 0.4–0.8% of all prostate cancers, is treated similarly to acinar adenocarcinoma but tends to have a higher likelihood of metastasis, recurrence, and poorer prognosis. Case presentation A 73-year-old Asian-Japanese male presented with gross hematuria, with investigations revealing a prostate ductal adenocarcinoma. Subsequent radical prostatectomy indicated a Gleason score of 8 with no lymph node metastasis. Despite initial prostate-specific antigen level reductions post-prostatectomy and salvage radiation therapy due to recurring elevated prostate-specific antigen levels, no recurrence was evident until 13 years later. A tumor in the anterior urethra was identified as metastasis of his prostate ductal adenocarcinoma. Conclusion This report presents an uncommon case of prostate ductal adenocarcinoma exhibiting a late recurrence in the anterior urethra 13 years post-radical prostatectomy.
Databáze: Directory of Open Access Journals
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