A Case of 'Cryptammonia': Disseminated Cryptococcal Infection Generating Profound Hyperammonemia in a Liver Transplant Recipient

Autor: Steven M. Phillips DO, Stephanie M. Pouch MD, Denise J. Lo MD, Sheetal Kandiah MD, Koba A. Lomashvili MD, Ram A. Subramanian MD, Peter Moran PharmD, Alley Killian PharmD, Prem A. Kandiah MD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Investigative Medicine High Impact Case Reports, Vol 10 (2022)
Druh dokumentu: article
ISSN: 2324-7096
23247096
DOI: 10.1177/23247096221129467
Popis: Mycoplasma and Ureaplasma infections have been described as a cause of hyperammonemia syndrome leading to devastating neurological injury in the post-transplant period, most commonly in lung transplant recipients. The occurrence of significant hyperammonemia caused by other urease-producing organisms remains unclear. We describe a case of disseminated cryptococcosis presenting with profound hyperammonemia in a 55-year-old orthotopic liver transplant recipient. Through a process of elimination, other potential causes for hyperammonemia were excluded revealing a probable association between hyperammonemia and disseminated cryptococcosis.
Databáze: Directory of Open Access Journals