Image-guided lung metastasis ablation: a literature review

Autor: Clara Prud’homme, Frederic Deschamps, Benjamin Moulin, Antoine Hakime, Marc Al-Ahmar, Salma Moalla, Charles Roux, Christophe Teriitehau, Thierry de Baere, Lambros Tselikas
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Hyperthermia, Vol 36, Iss 2, Pp 37-45 (2019)
Druh dokumentu: article
ISSN: 0265-6736
1464-5157
02656736
DOI: 10.1080/02656736.2019.1647358
Popis: Purpose: To review the available options of percutaneous ablation of lung metastasis. Methods: General indications, prognostic factors, and image guidance of percutaneous lung ablations were reviewed. Specificities, technical aspects, advantages and limitations of each technic were highlighted. Complications and follow up where also reviewed. Results: Image-guided, percutaneous ablation is of interest for patients with a limit number (90% for small tumors, and a very low complication rate. Microwave (MWA) and cryoablation are alternative technics developed in the last 15 years to overcome RFA limitations, with encouraging results. Larger ablations zones and less heat sink effect have been described with MWA. On the other hand, cryoablation allows painless treatments under conscious sedation and/or local anesthesia, high accessibility of difficult locations and promising results on prospective multicenter series. Although irreversible electroporation (IRE) could be used for lesions close to main blood vessels as it is not limited by the heat sink effect and does not have significant effects on connective tissue, allowing to treat lesions near to vital organs, preliminary results for lung metastasis are disappointing. Conclusion: Percutaneous ablation of lung metastases, whatever technic is used, is feasible, with high local control rate, and acceptable complication rate. Although indications seem clear enough, validation through controlled trials is mandatory.
Databáze: Directory of Open Access Journals
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